What is gastric lymphoma?
Gastric lymphoma is a rare malignant tumor that originates in the lymphoid tissue of the stomach. In recent years, with the advancement of medical technology and increasing health awareness, discussions about gastric lymphoma have gradually increased. This article will combine the hot topics and hot content on the Internet in the past 10 days to introduce you to the relevant knowledge of gastric lymphoma in detail.
1. Definition and classification of gastric lymphoma
Gastric lymphoma refers to a malignant tumor of the lymphatic system that originates in the stomach, accounting for 1%-5% of all gastric malignant tumors. According to the pathological type, gastric lymphoma is mainly divided into the following categories:
| Type | Proportion | Features |
|---|---|---|
| Mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) | about 50% | Closely related to Helicobacter pylori infection and slow growth |
| Diffuse large B-cell lymphoma (DLBCL) | about 30% | Strongly invasive and progresses quickly |
| Other types | about 20% | Including follicular lymphoma, T-cell lymphoma, etc. |
2. Causes and risk factors of gastric lymphoma
According to recent medical research, the main causes of gastric lymphoma include:
| risk factors | Related instructions |
|---|---|
| Helicobacter pylori infection | About 90% of patients with MALT lymphoma have infections |
| autoimmune disease | Such as Sjogren's syndrome, Hashimoto's thyroiditis, etc. |
| immunosuppressive state | Long-term use of immunosuppressants after organ transplantation |
| genetic factors | People with a family history of lymphoma are at increased risk |
3. Clinical manifestations of gastric lymphoma
The symptoms of gastric lymphoma are often atypical and can easily be confused with common gastric diseases. Recent clinical data shows that common patient symptoms include:
| Symptoms | incidence |
|---|---|
| Upper abdominal discomfort or pain | about 70% |
| Indigestion | about 60% |
| Nausea and vomiting | about 40% |
| weight loss | about 35% |
| gastrointestinal bleeding | about 25% |
4. Diagnostic Methods of Gastric Lymphoma
According to the latest diagnosis and treatment guidelines, the diagnosis of gastric lymphoma requires a combination of multiple examination methods:
| Check items | diagnostic value |
|---|---|
| Gastroscopy + biopsy | gold standard for diagnosis |
| Pathological immunohistochemistry | Determine lymphoma subtype |
| Helicobacter pylori detection | Guide treatment options |
| CT/PET-CT | Assess lesion extent and staging |
5. Progress in the treatment of gastric lymphoma
At a recent medical conference, experts shared the latest progress in the treatment of gastric lymphoma:
| Treatment | Applicable situations | efficient |
|---|---|---|
| Helicobacter pylori eradication treatment | early stage MALT lymphoma | About 70-80% |
| radiotherapy | local lesions | about 90% |
| Chemotherapy | Progressive cases | About 60-70% |
| targeted therapy | specific gene mutation | About 50-60% |
6. Prognosis and follow-up of gastric lymphoma
According to the latest follow-up data, the prognosis of gastric lymphoma is related to multiple factors:
| prognostic factors | 5 year survival rate |
|---|---|
| early stage MALT lymphoma | More than 90% |
| Limited stage DLBCL | 70-80% |
| Advanced DLBCL | 50-60% |
7. Prevention and health suggestions
Based on recent health science content, suggestions for preventing gastric lymphoma include:
1. Regularly screen for Helicobacter pylori, and treat those who are positive promptly.
2. Maintain good eating habits and avoid irritating foods
3. Pay attention to the symptoms of stomach discomfort and seek medical examination promptly.
4. Avoid long-term use of NSAIDs
5. Maintain a regular schedule and enhance immunity
Conclusion
Although gastric lymphoma is rare, its diagnosis and treatment have made significant progress with the development of medicine. By understanding relevant knowledge, maintaining a healthy lifestyle, and regular physical examinations, early detection and effective treatment can be achieved. If you have relevant symptoms, it is recommended to go to the gastroenterology or hematology department in time.
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