What happens when the endometrium sheds?
Endometrial shedding is a natural physiological process during the female menstrual cycle, usually directly related to the onset of menstruation. This phenomenon involves complex hormone regulation and physiological mechanisms, which will be explained in detail below through structured data and analysis.
1. Basic concepts of endometrial shedding

The endometrium is a layer of mucosal tissue covering the uterine cavity. It is regulated by estrogen and progesterone and will thicken and shed periodically. The shed endometrial fragments mix with blood and are expelled from the body to form menstruation.
| stage | Hormone changes | Endometrial status |
|---|---|---|
| proliferation phase | increased estrogen | Intima thickens to 3-5mm |
| secretory phase | Increased progesterone | The inner membrane can reach 8-12mm |
| shedding period | Hormone levels plummet | Intima disintegrates and falls off |
2. Popular related topics on the Internet in the past 10 days
According to recent Internet popularity monitoring, the following topics are closely related to endometrial health:
| Ranking | hot topics | focus of discussion |
|---|---|---|
| 1 | Menstrual health management | Natural remedies for menstrual cramps |
| 2 | endometriosis | New advances in diagnosis and treatment |
| 3 | Effects of birth control pills on the endometrium | Analysis of hormone regulation mechanism |
| 4 | artificial cycle therapy | IVF pre-treatment program |
3. Detailed mechanism of shedding process
1.hormone withdrawal signal: Luteal atrophy causes progesterone levels to decrease, triggering prostaglandin release
2.vasoconstrictive response: Spiral artery spasm causes intimal ischemic necrosis
3.tissue dissolution: Activation of matrix metalloproteinases (MMPs) leads to extracellular matrix degradation
4.discharge process: Uterine contractions help excreted tissue through the cervix
4. Common situations of abnormal shedding
| Type | clinical manifestations | Possible reasons |
|---|---|---|
| not completely shed | Prolonged menstruation/spotting | Luteal insufficiency |
| excessive shedding | Heavy menstrual bleeding | Uterine fibroids/adenomyosis |
| painful loss | severe dysmenorrhea | Excessive secretion of prostaglandins |
5. Health management suggestions
1.Nutritional supplements: Appropriate supplementation of iron and B vitamins to prevent anemia
2.moderate exercise: Yoga and other soothing exercises improve pelvic blood circulation
3.temperature regulation: Avoid abdominal cold during menstruation
4.medical examination: Abnormal bleeding requires ultrasound and six hormone tests
6. Warning symptoms that require medical treatment
✔ Non-menstrual vaginal bleeding
✔ The amount of menstrual blood is so heavy that it soaks through the sanitary napkin every hour
✔ Severe pain affecting daily life
✔ Menstrual cycle shorter than 21 days or longer than 35 days
Endometrial shedding is a barometer of female reproductive health, and understanding its physiological mechanism can help detect abnormalities early. It is recommended that every woman establish a menstrual file to record cycle characteristics and provide a basis for health management. When obvious abnormalities occur, a gynecologist should be consulted promptly for professional evaluation.
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